Stripes
Billings-Gagliardi, Susan
1R01 NS42271-01A
ES Blastocyst - Injected Shiverer Mice
These movie clips show the motor behavior of the three mice whose brains are illustrated in Figures 5 and 6 (pp. 30-31, and APPENDIX plates). You can view them as QuickTime or Media Player Movies.
A shiverer mouse for comparison
quicktime logo Quick Time
media player Media Player
Essentially Rescued (Figs. 5 and 6) This mouse has minimal tremor limited to the base of the tail and no gait ataxia. (Tremor is most obvious as the animal begins locomotion.)
quicktime logo Quick Time
media player Media Player
Intermediate (Figs. 5 and 6) This mouse has mild tremor involving the hindquarters as well as tail base. Although gait is somewhat ataxic, tail flinging is minimal.
quicktime logo Quick Time
media player Media Player
Minimally Rescued (Figs. 5 and 6) This mouse has significant tremor affecting much of its body and gait ataxia, which involves uneven strides, lateral rolling of the hindquarters, and some flinging of the tail. Behaviorally this mouse is similar to shiverer, although subtle differences were identified by an experienced observer (S.B.-G.).
quicktime logo Quick Time
media player Media Player
Essentially and Minimally Rescued Mice Together
quicktime logo Quick Time
media player Media Player
For further information or technical assistance contact Susan Billings-Gagliardi
Department of Cell Biology,
University of Massachusetts Medical School
55 Lake Avenue North, Worcester, MA 01655

Disclaimer: This is an unofficial UMMS page.