Wei Chen, MD, MS

Email: Wei.Chen@umassmed.edu
Phone: (508)856-8276
Academic Role: Instructor
UMass Program/Service Affiliations: Department of Psychiatry.
Specialty Areas: fMRI/MRS and Rehabilitation Medicine in brain disorders.


Dr. Chen is a Research Instructor of Psychiatry, University of Massachusetts Medical School. Her major research interests are to understand the signal sources of MRI/MRS and its applications as biomarkers for drug discovery and treatment evaluation of brain disorders , such as brain injury,dementia, mood disorders, ADHD, PTSD, Addiction, Autism ,Schizophrenia, etc.

Dr. Chen received her M.S. in Physical Medicine and Rehabilitation and M.D from Tongji Medical University (created by German physician Dr. Paulun in 1907) in China. She received her Second M.S. in Computer Science from Southeastern University at Washington, D.C. She completed a five years’ postdoctoral training in neuroimaging at CCNI , University of Massachusetts Medical School. Prior to joining the CCNI, She served as an attending physician at Department of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University in China.

Dr. Chen has been published in a number of Journals, including the Behavioral Brain Research, NeuroImage, Neuroscience Methods, stroke, and Archives of Physical Medicine and Rehabilitation. She was a member of International Society for Magnetic Resonance in Medicine, Society for Neuroscience.


Selected Publications:

  1. Wei Chen, Joseph R. DiFranza, and Jean A. King. Effect of Varenicline on BOLD and Neural Networks in Awake animals. 18th ISMRM-ESMRMB Joint Annual Meeting in Stockholm, Sweden. No. 1072, 2010.
  2. Wei Chen, Jessica Shields, Wei Huang and Jean King. Female Fear: Influence of Estrus Cycle on Behavioral Response and Neuronal Activation. Behav Brain Res. 2009 Jul 19; 201(1):8-13.
  3. Wei Chen, Joseph R. DiFranza, Wei. Huang and Jean A. King. Functional imaging of conditioned nicotine administration in an animal model of ADHD. Proc. 17th Intl. Soc. Mag. Reson. Med, Honolulu, Hawai'i, USA. No. 3730, 2009.
  4. Wei Chen, Elizabeth Rouse, David Olson and Jean A. King. Tracking the limbic-frontal glutamate system associated with aged emotion regulation. Proc. 17th Intl. Soc. Mag. Reson. Med, Honolulu, Hawai'i, USA. No. 1023, 2009.
  5. W. Chen, David Olson and Jean A. King. MRS identifies cortical neurochemical changes in “Parkinsonian” rats. Soc. Neurosci. 2007,445.3.
  6. Wei Chen, Jeff Tenney, Praveen Kulkarni and Jean A. King. Imaging unconditioned fear response with manganese-enhanced MRI (MEMRI). NeuroImage. 2007 August 1; 37(1): 221-229
  7. W. Chen, Praveen KulKarni, Timothy Garelick, and J. A. King.Fear and Aging: Role of Testosterone.Soc.Neurosci. 2006,576.13.
  8. Z. Li, W. Chen, P. Kulkarni, K. Murphy, J. Sullivan, J. A. King. Imaging nicotine response in an animal model of ADHD. Soc.Neurosci.2006,480.14.
  9. W. Chen, Y. Kim, K. F. Schmidt, F. Luo, M. Brevard, J. King. Neural Basis of Unconditional Fear: Perfusion and Functional Imaging in Aging Rat Bed Nucleus of the Stria Terminalis. Proc. 14th Intl. Soc. Mag. Reson. Med., Seattle, Washington, No.2129, 2006.
  10. J. A. Harder, T. S. Garelick, W. Chen, J. A. King. Imaging fear stress responses in monkeys. Proc. 14th Intl. Soc. Mag. Reson. Med., Seattle, Washington, No.2130, 2006.
  11. Sullivan, J.M., Jr., J.S. Mullen, U.A. Benz, K.F. Schmidt, M. Murugavel, W. Chen, and H. Ghadyani. Remote control of an MR imaging study via tele-collaboration tools. Proceedings Medical Imaging, Paper 5748-69, SPIE, San Diego, CA, February 2005.
  12. K. F. Schmidt, R. Lemdiasov, W. Chen, A. Obi, M. Brevard, M. Febo, F. Luo, J. King, T. Q. Duong, C. Ferris. Mapping changes in spin-echo BOLD and CBF in the conscious rat . Proc. 13th Intl. Soc. Mag. Reson. Med., Miami, FL, No.501, 2005.
  13. W. Chen, J. A. King, C. F. Ferris, P. Kulkarni, J. M. Sullivan. Odor- Induced Functional Imaging of Brain Activity in Conscious Animals. Proc. 13th Intl. Soc. Mag. Reson. Med., Miami, FL, No.1397, 2005.
  14. W. Chen, P. Kulkarni, J. A. King. Brain Activation Associated with the Re-experiencing a Fearful Event. Soc.Neurosci. 2005, 109.2.
  15. JA King, TS Garelick, ME. Brevard, W Chen, TL Messenger, T.Q. Duong, C.F. Ferris. Procedure for minimizing stress for fMRI studies in conscious rats. J Neurosci Methods. 2005 Oct 30;148(2):154-60
  16. H Ren, Q Shen, W Chen, TQ Duong. Delineation of Ischemic Tissue Fates using Improved Unsupervised ISODATA Clustering Technique, STROKE. 2004 Jan 35(1): 281.
  17. JR Tenney, W Chen, TQ Duong, JA King. Manganese-dependent contrast detection of brain activation in response to emotional stimuli. Proc.12th Intl. Soc. Mag. Reson. Med., Kyoto, Japan, 2004.
  18. Wei Chen , Timothy Garelick , Craig Ferris , Jean King. Age Effects on Regional Cerebral Blood Flow and Amygdala Activation in Response to Fear Stress .10 th Annual Meeting of the Organization for Human Brain Mapping. Budapest, Hungary. 2004.
  19. Wei Chen, Xiaohong Guo, Guoqiang Wang, Jianqun Ding, Lin Chen. The quality of life and rehabilitation in the patients following the breast cancer operation. Acta. Academ. Med. Hubei, 20:6-9, 1999.
  20. Wei Chen, Guoqiang Wang, Xiaohong Guo, Wantong Yang, Zhengcheng Guo. Assessment and analysis of cognitive dysfunction in CVA patients. Proceedings of 61st Annual Assembly of the American Academy of Physical Medicine and Rehabilitation in conjunction with the 13th World Congress of the International Federation of Physical Medicine and Rehabilitation. Washington, D. C. 1999. Arch. Phys. Med. Rehabil. , 80(9): 1205, 1999.
  21. Wei Chen, Guoqiang Wang. The rehabilitation of cognitive dysfunction in stroke patients. Proceedings of 11th Rehabilitation International Asia and the Pacific Regional Conference, Hong Kong, 1998.
  22. Wei Chen, Dexiu Zuo, Jianqun Ding, Dehua Zhou. The 26 cases' treatment of toe fracture using magnetic and manual therapy. Chinese Journal of Rehabilitation, 12(1):20, 1997.
  23. Lichang Li, Wei Chen. The diagnosis and treatment for acute lumbar sprain of athletes. Journal of Wuhan Institute of Physical Education, GS108:116, 1995.

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