Wei Chen, MD. M.S.

 
Center for Comparative Neuroimaging (CCNI),
Department of Psychiatry,
University of Massachusetts Medical School,
55 Lake Avenue, North
Worcester, MA, 01655
  Email:
Phone:
Wei.Chen@umassmed.edu
(508)856-8276

Education

02/2003-11/2008   Postdoctoral Training in Neuroimaging, CCNI, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, U.S.A.
09/2000-06/2002   Master of Science in Computer Science, Southeastern University (founded by Young Men's Christian Association in 1879), Washington, D.C. U.S.A.
09/1995-07/1998   Master of Medicine in Physical Medicine and Rehabilitation, Tongji Medical University (created by German physician Dr. Paulun in 1907), Wuhan, China.
09/1985-07/1990   M.D. (general practitioner), Tongji Medical University, Wuhan, China.


Teaching Experience

09/1998-09/2000   Assistant Professor of Rehabilitation Medicine, Department of Rehabilitation Medicine, Hubei Medical University(merged to Wuhan University) , Wuhan, China
09/1990-09/1995   Instructor of Rehabilitation Medicine, Department of Rehabilitation Medicine, Hubei Medical University(merged to Wuhan University), Wuhan, China

Professional Experience

Overview
Instructor of Research,Center for Comparative Neuroimaging (CCNI), Dept. of Psychiatry, University of Massachusetts Medical School, Worcester, MA, U.S.A 		 
MRI
Using blood-oxygen-level-dependent (BOLD) fMRI, perfusion imaging, quantitative Diffusion Weighted imaging (DWI), contrast agent imaging techniques to investigate brain mechanisms contributing to mental illness and drug addiction in the hope of improving psychosocial and psychopharmacologic intervention strategies. 		 
More
Apply multi-modality, multi-task noninvasive MRI/MR spectroscopy techniques to conduct translational imaging researches in psychiatry and neurology.

  • Hubei Medical University #2 Hospital, Wuhan, China (10/1996-09/2000)

Overview
Attending Physician, Department of Rehabilitation Medicine, Hubei Medical University #2 Hospital, Wuhan, China

Cancer treatment
Cancer treatment and rehabilitation: treated cancer patients, led and coordinated a multi-specialty physician team to develop new therapeutic approaches and rehabilitation methods. Primary investigator on a quality of life study for breast cancer patients. 		 
Cardiopulmonary Diseases
Treatment and rehabilitation of cardiopulmonary patients: implemented and supervised a treatment program specially designed for cardiopulmonary disease patients. Designed a measurement program to assess the effectiveness of therapeutic exercises prescribed for patients with cardiopulmonary diseases such as congestive heart failure /chronical heart failure.

Brain Injury
Brain injury rehabilitation: involved in treating brain injury patients with facilitating techniques and assessing traumatic brain injury functional outcomes with Functional Independence Measure (FIM) and Disability Rating Scale (DRS). 		 
Stroke Study
Treatment and rehabilitation of stroke patients: primary investigator in conducting a clinical study to compare the outcomes of different therapeutic methods for stroke patients with specific focuses on determining the degree of impairment and disability, evaluating psychosocial and vocational factors, assessing motor and cognitive functions.

  • Tongji Medical University, Wuhan, China (09/1995-07/1998)

Overview
Research Fellow, Department of Rehabilitation Medicine, Tongji Medical University, Wuhan, China 		 
Investigator
Primary investigator in research and studies related to brain damage in stroke patients such as the mechanism that leads to brain damage in stroke patients, neuronal development and plasticity, and brain protection. 		 
Other Topics
Other topics researched during this period included cognitive dysfunction of cerebrovascular accident patients and assessment methods of cognitive dysfunction. Using Blessed Dementia Scales (BDS), Halstead-Reitan-Battery -Revised in China (H.R.B-RC), Wechsler Adult Intelligence Scale-Revised in China (WAIS-RC) and cognition subscales of Functional Independence Measure (FIM) to evaluate the cognitive function of the cerebrovascular accident patients.

  • Resident/Physician, Department of Rehabilitation Medicine, Hubei Medical University #2 Hospital, Wuhan, China (09/1990-09/1995)

Professional Membership

Publication

  1. Wei Chen, Jessica Shields, Wei Huang and Jean King. Female Fear: Influence of Estrus Cycle on Behavioral Response and Neuronal Activation. Behav Brain Res. 2009 Jul 19; 201(1):8-13.
  2. Wei Chen, Joseph R. DiFranza, Wei. Huang and Jean A. King. Functional imaging of conditioned nicotine administration in an animal model of ADHD. Proc. 17th Intl. Soc. Mag. Reson. Med, Honolulu, Hawai'i, USA. No. 3730, 2009.
  3. Wei Chen, Elizabeth Rouse, David Olson and Jean A. King. Tracking the limbic-frontal glutamate system associated with aged emotion regulation. Proc. 17th Intl. Soc. Mag. Reson. Med, Honolulu, Hawai'i, USA. No. 1023, 2009.
  4. W. Chen, David Olson and Jean A. King. MRS identifies cortical neurochemical changes in “Parkinsonian” rats. Soc. Neurosci. 2007,445.3.
  5. Wei Chen, Jeff Tenney, Praveen Kulkarni and Jean A. King. Imaging unconditioned fear response with manganese-enhanced MRI (MEMRI). NeuroImage. 2007 August 1; 37(1): 221-229
  6. W. Chen, Praveen KulKarni, Timothy Garelick, and J. A. King.Fear and Aging: Role of Testosterone.Soc.Neurosci. 2006,576.13.
  7. Z. Li, W. Chen, P. Kulkarni, K. Murphy, J. Sullivan, J. A. King. Imaging nicotine response in an animal model of ADHD. Soc.Neurosci.2006,480.14.
  8. W. Chen, Y. Kim, K. F. Schmidt, F. Luo, M. Brevard, J. King. Neural Basis of Unconditional Fear: Perfusion and Functional Imaging in Aging Rat Bed Nucleus of the Stria Terminalis. Proc. 14th Intl. Soc. Mag. Reson. Med., Seattle, Washington, No.2129, 2006.
  9. J. A. Harder, T. S. Garelick, W. Chen, J. A. King. Imaging fear stress responses in monkeys. Proc. 14th Intl. Soc. Mag. Reson. Med., Seattle, Washington, No.2130, 2006.
  10. Sullivan, J.M., Jr., J.S. Mullen, U.A. Benz, K.F. Schmidt, M. Murugavel, W. Chen, and H. Ghadyani. Remote control of an MR imaging study via tele-collaboration tools. Proceedings Medical Imaging, Paper 5748-69, SPIE, San Diego, CA, February 2005.
  11. K. F. Schmidt, R. Lemdiasov, W. Chen, A. Obi, M. Brevard, M. Febo, F. Luo, J. King, T. Q. Duong, C. Ferris. Mapping changes in spin-echo BOLD and CBF in the conscious rat . Proc. 13th Intl. Soc. Mag. Reson. Med., Miami, FL, No.501, 2005.
  12. W. Chen, J. A. King, C. F. Ferris, P. Kulkarni, J. M. Sullivan. Odor- Induced Functional Imaging of Brain Activity in Conscious Animals. Proc. 13th Intl. Soc. Mag. Reson. Med., Miami, FL, No.1397, 2005.
  13. W. Chen, P. Kulkarni, J. A. King. Brain Activation Associated with the Re-experiencing a Fearful Event. Soc.Neurosci. 2005, 109.2.
  14. JA King, TS Garelick, ME. Brevard, W Chen, TL Messenger, T.Q. Duong, C.F. Ferris. Procedure for minimizing stress for fMRI studies in conscious rats. J Neurosci Methods. 2005 Oct 30;148(2):154-60
  15. H Ren, Q Shen, W Chen, TQ Duong. Delineation of Ischemic Tissue Fates using Improved Unsupervised ISODATA Clustering Technique, STROKE. 2004 Jan 35(1): 281.
  16. JR Tenney, W Chen, TQ Duong, JA King. Manganese-dependent contrast detection of brain activation in response to emotional stimuli. Proc.12th Intl. Soc. Mag. Reson. Med., Kyoto, Japan, 2004.
  17. Wei Chen , Timothy Garelick , Craig Ferris , Jean King. Age Effects on Regional Cerebral Blood Flow and Amygdala Activation in Response to Fear Stress .10 th Annual Meeting of the Organization for Human Brain Mapping. Budapest, Hungary. 2004.
  18. Wei Chen, Pam Graybeil, Victoria Rossi, Jeffrey Tenney and Jean A. King. Female Fear: Brain Activation across the Estrus Cycle. Soc.Neurosci. 2004,1025.6. (Neuroscience 2004- the Annual Meeting Press Book Part(2), page 1071.)
  19. Wei Chen, Xiaohong Guo, Guoqiang Wang, Jianqun Ding, Lin Chen. The quality of life and rehabilitation in the patients following the breast cancer operation. Acta. Academ. Med. Hubei, 20:6-9, 1999.
  20. Wei Chen, Guoqiang Wang, Xiaohong Guo, Wantong Yang, Zhengcheng Guo. Assessment and analysis of cognitive dysfunction in CVA patients. Proceedings of 61st Annual Assembly of the American Academy of Physical Medicine and Rehabilitation in conjunction with the 13th World Congress of the International Federation of Physical Medicine and Rehabilitation. Washington, D. C. 1999. Arch. Phys. Med. Rehabil. , 80(9): 1205, 1999.
  21. Wei Chen, Guoqiang Wang. The rehabilitation of cognitive dysfunction in stroke patients. Proceedings of 11th Rehabilitation International Asia and the Pacific Regional Conference, Hong Kong, 1998.
  22. Wei Chen, Dexiu Zuo, Jianqun Ding, Dehua Zhou. The 26 cases' treatment of toe fracture using magnetic and manual therapy. Chinese Journal of Rehabilitation, 12(1):20, 1997.
  23. Wei Chen.The long-term outcome of breast cancer operation: implications for service planning. Proceedings of the 8th World Congress of the International Rehabilitation Medicine Association, Japan. 1997.
  24. Lichang Li, Wei Chen. The diagnosis and treatment for acute lumbar sprain of athletes. Journal of Wuhan Institute of Physical Education, GS108:116, 1995.

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Last modified: 04/26/2009 by Wei Chen.

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